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Enum: SampleComponentRoleEnum

Part a component plays in a sample. A superset of SampleProteinRoleEnum and SampleNucleicAcidRoleEnum, so a role given on an association can be repeated on the component without translation.

URI: lambda:SampleComponentRoleEnum

Permissible Values

Value Meaning Description
target None The thing under investigation
subunit None One subunit or strand of a complex that is the target as a whole
binding_partner None A macromolecule present for its interaction with the target: an antibody, a s...
ligand None A small molecule present for its binding to the target, where a more specific...
substrate None A substrate of an enzyme in the sample, including a non-hydrolysable analogue
product None A product of an enzyme in the sample
inhibitor None A small molecule or macromolecule that inhibits the target
activator None A small molecule or macromolecule that activates the target
cofactor None A cofactor, coenzyme, prosthetic group or structural metal ion of the target
fusion_partner None A solubility or affinity fusion partner left attached (e
chaperone None A chaperone or scaffold added to stabilize or reconstitute the target
template None The strand a polymerase or reverse transcriptase reads
primer None The strand a polymerase extends
guide None A guide RNA or DNA that directs a nuclease or other effector to its target
scaffold None A structural scaffold, as in DNA origami or a nanoparticle assembly
carrier None A nanodisc, micelle, liposome or other host that holds a membrane protein
additive None A cryoprotectant, precipitant, reducing agent or other additive that is part ...
contaminant None Present unintentionally and identified after the fact
standard None A reference added for calibration or as a size marker

Slots

Name Description
role Part this component plays in the sample

Identifier and Mapping Information

Schema Source

  • from schema: http://w3id.org/lambda/

LinkML Source

name: SampleComponentRoleEnum
description: Part a component plays in a sample. A superset of SampleProteinRoleEnum
  and SampleNucleicAcidRoleEnum, so a role given on an association can be repeated
  on the component without translation.
from_schema: http://w3id.org/lambda/
rank: 1000
permissible_values:
  target:
    text: target
    description: The thing under investigation
  subunit:
    text: subunit
    description: One subunit or strand of a complex that is the target as a whole
  binding_partner:
    text: binding_partner
    description: 'A macromolecule present for its interaction with the target: an
      antibody, a substrate protein, the DNA site a transcription factor binds'
  ligand:
    text: ligand
    description: A small molecule present for its binding to the target, where a more
      specific role does not apply
  substrate:
    text: substrate
    description: A substrate of an enzyme in the sample, including a non-hydrolysable
      analogue
  product:
    text: product
    description: A product of an enzyme in the sample
  inhibitor:
    text: inhibitor
    description: A small molecule or macromolecule that inhibits the target
  activator:
    text: activator
    description: A small molecule or macromolecule that activates the target
  cofactor:
    text: cofactor
    description: A cofactor, coenzyme, prosthetic group or structural metal ion of
      the target
  fusion_partner:
    text: fusion_partner
    description: A solubility or affinity fusion partner left attached (e.g., MBP,
      GST, GFP)
  chaperone:
    text: chaperone
    description: A chaperone or scaffold added to stabilize or reconstitute the target
  template:
    text: template
    description: The strand a polymerase or reverse transcriptase reads
  primer:
    text: primer
    description: The strand a polymerase extends
  guide:
    text: guide
    description: A guide RNA or DNA that directs a nuclease or other effector to its
      target
  scaffold:
    text: scaffold
    description: A structural scaffold, as in DNA origami or a nanoparticle assembly
  carrier:
    text: carrier
    description: A nanodisc, micelle, liposome or other host that holds a membrane
      protein
  additive:
    text: additive
    description: A cryoprotectant, precipitant, reducing agent or other additive that
      is part of the sample rather than of the buffer
  contaminant:
    text: contaminant
    description: Present unintentionally and identified after the fact
  standard:
    text: standard
    description: A reference added for calibration or as a size marker